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A5156
Sigma
Actinomycin D–Mannitol
lyophilized powder
| MDL number: | MFCD00216815 |
Description
| Components | 1 mg actinomycin D and 49 mg mannitol per vial |
| Biochem/physiol Actions | An antineoplastic antibiotic that inhibits cell proliferation by forming a stable complex with DNA and blocking the movement of RNA polymerase which interferes with DNA-dependent RNA synthesis. Induces apoptosis. Potent antitumor agent. For cell culture applications, actinomycin D is used as a selection agent and is used in banding techniques to differentiate between different regions of chromosomes. |
Properties
| form | lyophilized powder |
| solubility | H2O: 20 mg/mL |
| storage temp. | 2-8°C |
Safety
| Personal Protective Equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
| Hazard Codes | T+ |
| Risk Statements | 28-40-42/43 |
| Safety Statements | 22-28-36/37-45 |
| RIDADR | UN2811 6.1/PG 2 |
| WGK Germany | 3 |
